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Allele : Tg(Myh6-MYL2*R58Q)#Dsc transgene insertion, Danuta Szczesna-Cordary

Primary Identifier  MGI:4820518 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(Myh6-MYL2*R58Q)#Dsc
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  The human ventricular myosin regulatory light chain with with an arginine to glutamine substitution at amino acid 58 (R58Q, a familial hypertrophic cardiomyopathy-linked mutation) is under the control of about 5.5 kb of the mouse alpha-myosin heavy chain promoter which includes the first two exons and part of the third. Two lines (9 and 8) were generated, however the pound symbol (#) is used when line is not specified or lines are pooled.
  • mutations:
  • Insertion
  • synonyms:
  • Tg-R58Q,
  • Tg-R58Q
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

9 Publication categories