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Allele : Traf3ip2<adjm> TRAF3 interacting protein 2; atopic dermatitis from Japanese mice

Primary Identifier  MGI:4820827 Allele Type  Spontaneous
Gene  Traf3ip2 Inheritance Mode  Recessive
Strain of Origin  KOR Is Recombinase  false
Is Wild Type  false
molecularNote  A spontaneous mutation resulted in a C to T transition in the second exon. The transition results in a C- terminal truncation by changing amino acid 214 from glutamine (CAG) to a stop codon (TAG). RT-PCR showed reduced transcript level and western blots of protein extracts from spleens showed no specific Ab labeling in the positions expected for TRAF3IP2.
  • mutations:
  • Nucleotide substitutions
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

8 Carried By

0 Driven By

2 Publication categories