Primary Identifier | MGI:4820827 | Allele Type | Spontaneous |
Gene | Traf3ip2 | Inheritance Mode | Recessive |
Strain of Origin | KOR | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A spontaneous mutation resulted in a C to T transition in the second exon. The transition results in a C- terminal truncation by changing amino acid 214 from glutamine (CAG) to a stop codon (TAG). RT-PCR showed reduced transcript level and western blots of protein extracts from spleens showed no specific Ab labeling in the positions expected for TRAF3IP2. |