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Allele : Jak2<tm1.1Jlvl> Janus kinase 2; targeted mutation 1.1, Jean-Luc Villeval

Primary Identifier  MGI:4829538 Allele Type  Targeted
Attribute String  Humanized sequence Gene  Jak2
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 13 was replaced with one in which a G to T mutation results in an amino acid substitution of phenylalanine for valine at position 617 (V617F). An FRT flanked neo cassette downstream of the modified exon was removed by flp mediated recombination.
  • mutations:
  • Single point mutation,
  • Insertion
  • synonyms:
  • Jak2<V617F>,
  • Jak2<V617F>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories