Primary Identifier | MGI:4829629 | Allele Type | Chemically induced (ENU) |
Gene | Gon4l | Inheritance Mode | Recessive |
Strain of Origin | C3HeB/FeJ | Is Recombinase | false |
Is Wild Type | false |
molecularNote | ENU mutagenesis induced a T to A transversion producing a cryptic splice site in intron 24 that results in the production of an expanded transcript. This modified transcript contains 81 additional nucleotides, including two premature stop codons. The absence of protein expression was confirmed by western blot analysis on cell lysates. |