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Allele : Tg(KRT14-Ptch1)#Abal transgene insertion, Allan Balmain

Primary Identifier  MGI:4830587 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(KRT14-Ptch1)#Abal
Strain of Origin  FVB/N Is Recombinase  false
Is Wild Type  false
molecularNote  An HA-tagged Ptch1 sequence from C57BL/6 was modified to encode the Threonine to Asparagine sustitution at amino acid residue 1267 which is found in FVB/N strains. Residue 1267 is found in a conserved region of the cytoplasmic domain near the C-terminus. The modified sequence was placed under the control of the human KRT14 promoter. At least four founder lines were produced (numbers 6, 7, 8, 10).
  • mutations:
  • Insertion
  • synonyms:
  • K14Ptch<FVB>,
  • K14Ptch<FVB>
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories