| Primary Identifier | MGI:4830258 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Col2a1 |
| Transmission | Germline | Strain of Origin | 129X1/SvJ |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exon 2 was replaced with a floxed neo cassette via homologous recombination. Cre mediated recombination removed the neo cassette. RT-PCR analysis confirmed the absence of the IIA transcript and continued expression of the IIB transcript in E9.5 homozygous embryos. This is an isoform specific knock-out. |