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Allele : Col2a1<tm1.1Ksec> collagen, type II, alpha 1; targeted mutation 1.1, Kathryn S E Cheah
Primary Identifier  MGI:4830258 Allele Type  Targeted
Attribute String  Null/knockout Gene  Col2a1
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 2 was replaced with a floxed neo cassette via homologous recombination. Cre mediated recombination removed the neo cassette. RT-PCR analysis confirmed the absence of the IIA transcript and continued expression of the IIB transcript in E9.5 homozygous embryos. This is an isoform specific knock-out.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • IIA<->,
  • IIA<->
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1 Feature

Trail: Allele

Genome

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0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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