| Primary Identifier | MGI:4830522 | Allele Type | Targeted |
| Gene | Cyp1a1 | Transmission | Germline |
| Strain of Origin | 129X1/SvJ | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Exon 2 was replaced with a modified exon 2 in which nucleotide substitutions (AGA to GAC at codon 34 and AAA to ATA at codon 39) result in the amino acid substitutions of aspartic acid for arginine at position 34 (R34D) and isoleucine for lysine at position 39 (K39I) within the mitochondrial targeting domain. A floxed neo cassette inserted upstream of the modified exon was removed by cre mediated recombination. The product is predicted to undergo ER-specific targeting. |
