| Primary Identifier | MGI:4834775 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Smo |
| Transmission | Germline | Strain of Origin | 129X1/SvJ |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | LoxP sites and an frt-flanked neomycin resistance cassette were inserted flanking the first coding exon. A tau-LacZ gene was also inserted 3' to the neomycin resistance gene. A null allele was generated by crossing the loxP-flanked allele to beta-actin-Cre expressing mice, an allele with germline Cre expression, and subsequently crossing out the Cre transgene by backcrossing to ICR. |
