| Primary Identifier | MGI:4835263 | Allele Type | Targeted |
| Gene | Plp1 | Transmission | Germline |
| Strain of Origin | Not Specified | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The splice donor site at the 3' end of exon 3 was inactivated by site directed mutagenesis. A floxed PGKneo selection cassette was then inserted at position 49 of intron 3. Cre expression was used to remove the floxed neo cassette permitting the expression of the DM-20 isoform but not the full length product. |
