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Allele : Ptk2<tm1.1Itl> PTK2 protein tyrosine kinase 2; targeted mutation 1.1, inGenious Targeting Laboratory

Primary Identifier  MGI:4837147 Allele Type  Targeted
Gene  Ptk2 Transmission  Germline
Strain of Origin  C57BL/6 x 129S/SvEv Is Recombinase  false
Is Wild Type  false
molecularNote  Exon 21 (or exon 18 depending on transcript) was replaced with one in which an A to G point transition results in the replacement of lysine with arginine at position 454 (K454R). An FRT flanked neo cassette inserted downstream of the modified exon 21 was removed by flp mediated recombination.
  • mutations:
  • Single point mutation,
  • Insertion
  • synonyms:
  • Ptk2<L454R>,
  • FAK<R454>,
  • FAK<R454>,
  • FAK<KD>,
  • Ptk2<tm1.1Igl>,
  • Ptk2<tm1.1Igl>,
  • Ptk2<L454R>,
  • FAK<KD>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

8 Publication categories