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Allele : Pdpk1<tm1.1Daca> 3-phosphoinositide dependent protein kinase 1; targeted mutation 1.1, Doreen A Cantrell

Primary Identifier  MGI:4838167 Allele Type  Targeted
Gene  Pdpk1 Transmission  Germline
Strain of Origin  129P2/OlaHsd Is Recombinase  false
Is Wild Type  false
molecularNote  Exon 4 was replaced with one in which nucleotide substitution resulted in the amino acid substitution of alanine for lysine at position 111 (K111A) and a neo cassette. Cre mediated recombination removed the neo cassette. The absence of catalytic activity was confirmed in E11.5 to E12.5 embryo lysates despite confirmed protein expression.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • PDK1<K111A>,
  • PDK1<K111A>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories