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Allele : Mdm2<tm3.1Glo> transformed mouse 3T3 cell double minute 2; targeted mutation 3.1, Guillermina Lozano

Primary Identifier  MGI:4835494 Allele Type  Targeted
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Mdm2
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  Intron 1 was replaced with the corresponding human intron 1 with a G in position 309. A floxed neo cassette was also inserted into intron 3 and then removed via Cre mediated recombination. RT-PCR analysis indicated higher levels of RNA expression in spleens and thymi from homozygous mice relative to wild-type mice.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Mdm2<SNP309G>,
  • Mdm2<SNP309G>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

6 Publication categories