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Allele : Rr152<tm5.1Cog> regulatory region 152; targeted mutation 5.1, Michel Cogne
Primary Identifier  MGI:4836663 Allele Type  Targeted
Attribute String  Modified regulatory region Gene  Rr152
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site flanked neomycin resistance gene cassette replaced the entire 3' regulatory region (3'RR, located downstream of the Ighc gene segments)(Rr152), which contains the enhancers hs3a (Rr154), hs1,2 (Rr153), hs3b (Rr155) and hs4 (Rr156). Cre-mediated recombination removed the neo cassette.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • IgH a<delta3'RR>,
  • IgH a<delta3'RR>,
  • delta3'RR,
  • delta3'RR,
  • IgH 3'RR<->,
  • 3'RRKO,
  • 3'RRKO,
  • IgH 3'RR<->,
  • Igh<tm5.1Cog>,
  • Igh<tm5.1Cog>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

23 Publication categories





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