| Primary Identifier | MGI:4837622 | Allele Type | Spontaneous |
| Attribute String | Null/knockout | Gene | Irs1 |
| Transmission | Germline | Strain of Origin | 129S2/SvPas |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A spontaneous mutation produced a C-to-A transition that results in an amino acid substitution of serine to stop codon at position 57 (p.S57*). The absence of protein expression was confirmed by western blot analysis on muscle extracts. |