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Allele : Irs1<smla> insulin receptor substrate 1; small phenotype

Primary Identifier  MGI:4837622 Allele Type  Spontaneous
Attribute String  Null/knockout Gene  Irs1
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  A spontaneous mutation produced a C-to-A transition that results in an amino acid substitution of serine to stop codon at position 57 (p.S57*). The absence of protein expression was confirmed by western blot analysis on muscle extracts.
  • mutations:
  • Single point mutation
  • synonyms:
  • Irs1<S57X>,
  • Irs1<S57X>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

8 Publication categories

Trail: Allele