| Primary Identifier | MGI:4838016 | Allele Type | Targeted |
| Attribute String | Recombinase | Gene | Hand1 |
| Transmission | Germline | Strain of Origin | 129S/SvEv |
| Is Recombinase | true | Is Wild Type | false |
| molecularNote | A targeting vector containing a 3.4 kb EGFP/cre cassette with a 3' Frt-flanked neomycin cassette was introduced into the 5' untranslated region of Hand1. Homologous recombination resulted in deletion of the first exon of Hand1, producing a null allele, and insertion of the EGFP/cre gene under control of the endogenous promoter. Following germline transmission, the neo cassette was deleted by crossing mice to FLPeR homozygous mice. |
