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Allele : Cacna1b<tm2.1Dili> calcium channel, voltage-dependent, N type, alpha 1B subunit; targeted mutation 2.1, Diane Lipscombe

Primary Identifier	MGI:4838019	Allele Type	Targeted
Gene	Cacna1b	Transmission	Germline
Strain of Origin	129P2/OlaHsd	Is Recombinase	false
Is Wild Type	false

molecularNote

Using MICER clone MHPN59f07, exon 37a was replaced with a modified exon 37b, which lacked the XhoI restriction site, and a floxed neo cassette. Cre mediated recombination removed the neo cassette.

mutations:
Intragenic deletion

cellLines:
Not Specified

synonyms:
Cacna1b<b*b>,
Cacna1b<b*b>

earliestPublication:
Andrade A, et al. (2010) Opioid inhibition of N-type Ca2+ channels and spinal analgesia couple to alternative splicing. Nat Neurosci 13(10):1249-56

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

6 Publication categories

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