| Primary Identifier | MGI:4838549 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Nox4 |
| Transmission | Germline | Strain of Origin | 129/Sv |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site was inserted upstream of exon 1 and an FRT flanked neo cassette and second loxP site were inserted downstream of exon 2 via homologous recombination. Recombinase mediated recombination removed exons 1 and 2 and the neo cassette. Western blot analysis confirmed the absence of protein expression in the hearts and kidneys of homozygous mice. |
