| Primary Identifier | MGI:4838417 | Allele Type | Targeted |
| Attribute String | Inducible, Recombinase | Gene | Etv1 |
| Transmission | Germline | Strain of Origin | C57BL/6 |
| Induced With | tamoxifen | Is Recombinase | true |
| Is Wild Type | false | Project Collection | Neuroscience Blueprint cre |
| molecularNote | A targeting vector was designed to insert a Cre/ERT2 fusion gene , an SV40 polyA signal, and an frt-flanked neo cassette into the initiation codon of the ets variant gene 1 locus (Etv1). This construct was electroporated into C57BL/6-derived embryonic stem (ES) cells. Correctly targeted ES cells were injected into recipient blastocysts and chimeric mice were bred with white C57BL/6 mice (harboring the Tyrc-2J mutation) to originate the colony. Mutant mice were bred with Actin-FLPe mice (on a C57BL/6 congenic background) to remove the neo selection cassette. |
