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Allele : Med12<tm1.2Hsch> mediator complex subunit 12; targeted mutation 1.2, Heinrich Schrewe

Primary Identifier  MGI:4839486 Allele Type  Targeted
Attribute String  Null/knockout Gene  Med12
Transmission  Chimeric Strain of Origin  (129S6/SvEvTac x C57BL/6NCrl)F1
Is Recombinase  false Is Wild Type  false
molecularNote  One loxP site was inserted in the 5'UTR of exon 1 while a second loxP site, followed by an FRT flanked neomycin cassette in reverse orientation, was inserted in intron 7. The selection cassette was subsequently removed by transient flp recombinase expression leaving exons 1-7 flanked by loxP sites. Transient cre expression then excised the floxed exons.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Med12<delta1-7>,
  • Med12<delta1-7>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories