| Primary Identifier | MGI:4842905 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Notch4 |
| Transmission | Germline | Strain of Origin | C57BL/6NTac |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | KOMP-Regeneron |
| molecularNote | The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 23547bp between positions 34783423-34806969 of Chromosome 17 (Build GRCm39). The entire coding region was replaced with a lacZ/neo cassette inserted between the start and stop codons, thus creating a null allele. Whole-mount immunofluorescence confirmed detection of anti-NOTCH4 extracellular domain reactivity in the vasculature of wild-type but not homozygous mutant P5 retinas. |
