| Primary Identifier | MGI:4847629 | Allele Type | Targeted |
| Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Ctsg |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A cDNA encoding the human PML-RARA fusion with nucleotide substitution resulting in the amino acid substitutions of arginine for valine at positions 420 and 432 (V420 and V423R) was inserted into the 5'UTR along with a floxed neo cassette. Cre-mediated recombination removed the neo cassette. The amino acid substitutions generate a protease cleavage-resistant PML-RARA product. |
