Primary Identifier | MGI:4849506 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Magel2 |
Transmission | Germline | Strain of Origin | 129S2/SvPas |
Is Recombinase | false | Is Wild Type | false |
description | Magel2 is only expressed paternally (imprinted maternally). |
molecularNote | The 5' portion of the coding region was replaced with a floxed hygro cassette. Cre-mediated recombination removed the hygro cassette. The absence of expression in the brain was confirmed by immunohistochemistry. |