| Primary Identifier | MGI:4868726 | Allele Type | Targeted |
| Attribute String | Conditional ready, No functional change | Gene | Hes1 |
| Transmission | Germline | Strain of Origin | B6.Cg-Thy1<a> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Tow loxP sites were inserted to flank part of intron 1, exons 2-4 and the 3'UTR. An FRT site-flanked neomycin resistance gene was introduced followed by the second loxP site, and removed later by Flp-mediated recombination. A beta-galactosidase gene was also inserted after the second loxP site. Cre-mediated recombination of the loxP-flanked gene segment creates an in frame translation of beta-galactosidase. |
