| Primary Identifier | MGI:4868408 | Allele Type | Transgenic |
| Attribute String | Recombinase | Gene | Tg(Pax4-cre)1Dam |
| Strain of Origin | (C57BL/6 x CBA)F1 | Is Recombinase | true |
| Is Wild Type | false |
| description | These Pax4-cre transgenic mice function only for cre recombinase expression in Pax4-expressing cells (no tet-Off or fluorescence function is reported). The transgene was microinjected into fertilized (C57BL/6 X CBA)F1 oocytes, and founder mice were bred to ICR outbred mice to establish a colony. |
| molecularNote | The Pax4-cre transgene was designed with the mouse paired box gene 4 (Pax4) promoter directing expression of an enhanced green fluorescent protein fused to a tet-off cassette (EGFP/tTA). The transgene also contained a tetracycline-responsive element witha CMV minimal promoter (tetO-CMVmin) driving expression of a cre-recombinase. |
