| Primary Identifier | MGI:4878880 | Allele Type | Targeted |
| Attribute String | No functional change | Gene | Cngb1 |
| Transmission | Germline | Strain of Origin | 129/Sv |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The nucleotides within exon 20 encoding for 14 amino acids in the calmodulin binding domain were removed and a floxed neo cassette was inserted into intron 19 via homologous recombination. Cre mediated recombination removed the neo cassette. Western blot analysis did not detect a change in the level of protein expression in the retinas of homozygous mice compared to wild-type controls. The mutant protein is located in the outer rod segments similar to the wild-type protein. |
