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Allele : Triobp<tm1Tbf> TRIO and F-actin binding protein; targeted mutation 1, Thomas B Friedman

Primary Identifier  MGI:4881773 Allele Type  Targeted
Attribute String  Modified isoform(s), Null/knockout, Reporter Gene  Triobp
Transmission  Germline Strain of Origin  B6.Cg-Thy1<a>
Is Recombinase  false Is Wild Type  false
molecularNote  Nearly all of exon 8 was replaced by a nlacZ reporter cassette and a floxed neo cassette, which was removed by cre-mediated recombination. The absence of isoform 5 transcript and isoform 4/5 proteins in the inner ear was confirmed by RT-PCR and western blot analysis respectively. Isoform 1 is retained.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Triobp<deltaexon8>,
  • Triobp<deltaexon8>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

7 Publication categories