Primary Identifier | MGI:4888599 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(MAPT*S305S)4Gds |
Strain of Origin | Not Specified | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The transgene contains the complete sequence of human MAPT gene as contained in the P1 artificial chromosome (PAC) 61D6 (Research Genetics, Huntsville, AL). This downstream segment contains the 3 prime end of the gene KIAA1267. MAPT is the only complete gene on this PAC. The S305S mutation was introduced into this PAC using a 2- step recombineering process. |