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Allele : Tg(UBC-TVA)1Clc transgene insertion 1, Constance L Cepko

Primary Identifier	MGI:4888011	Allele Type	Transgenic
Attribute String	Inserted expressed sequence	Gene	Tg(UBC-TVA)1Clc
Strain of Origin	(C57BL/6 x SJL/J)F2	Is Recombinase	false
Is Wild Type	false

molecularNote

The TVA transgene was designed with the human ubiquitin C (UBC) promoter driving expression of a loxP-flanked green fluorescent protein (GFP) and polyadenylation sequence, followed by an avian specific retroviral receptor (TVA) gene derived from quail. Cre-mediated recombination removed the floxed GFP.

mutations:
Insertion

earliestPublication:
Beier KT, et al. (2011) Conditional expression of the TVA receptor allows clonal analysis of descendents from Cre-expressing progenitor cells. Dev Biol 353(2):309-20

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

3 Publication categories

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