Primary Identifier | MGI:4888391 | Allele Type | Transgenic |
Attribute String | Recombinase | Gene | Tg(Vav1-cre)8Cgp |
Strain of Origin | Not Specified | Is Recombinase | true |
Is Wild Type | false |
molecularNote | An SV40 intron, cre recombinase cDNA and an SV40 polyA cassette were inserted into a vector behind the Vav1 promoter. The construct was injected into pronuclei to generate transgenic mice. 2 lines, 1 and 8, resulted and both exhibited recombination in the majority of hematopoietic and endothelial cells but very little in other somatic cells. |