|  Help  |  About  |  Contact Us

Allele : Tg(Prnp-ATXN3*79Q)#Hlw transgene insertion, Hung-Li Wang

Primary Identifier  MGI:4940057 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(Prnp-ATXN3*79Q)#Hlw
Strain of Origin  FVB/N Is Recombinase  false
Is Wild Type  false
molecularNote  The mouse promoter drive neuronal expression of the HA-tagged human cDNA with a trinucleotide repeat that results in a 79 glutamine stretch. This amplification of the glutamine tract is associated with Spinocerebellar Ataxia 3 (SCA3) in humans. Two lines with more than five copies of the transgene were generated. The pound symbol (#) denotes when no line number is specified and/or lines are pooled.
  • mutations:
  • Insertion
  • synonyms:
  • Ataxin-3-Q79,
  • Ataxin-3-Q79
Quick Links:
 
Quick Links:
 

1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

5 Publication categories