| Primary Identifier | MGI:4940851 | Allele Type | Targeted |
| Attribute String | Null/knockout, Recombinase | Gene | Il17a |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | true | Is Wild Type | false |
| molecularNote | A codon-improved cre recombinase gene, preceded by a 5-codon linker sequence and followed by an SV40 intron and poly(A) signal sequences, was inserted immediately after the endogenous start codon in exon 1. Point mutations were introduced into exon 2 of the Il17a gene to disable an internal ATG-site. The neomycin resistance gene cassette that was inserted downstrea of the cre gene was excised by FLPe-mediated recombination to generate the the final allele. |
