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Allele : Gt(ROSA)26Sor<tm1(Pim1-E2F1)Rebr> gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Rene Bernards

Primary Identifier  MGI:4940857 Allele Type  Targeted
Attribute String  Conditional ready, Humanized sequence, Inserted expressed sequence, Reporter Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A human E2F1 cDNA was cloned downstream of a murine Pim1 promoter with a duplicated Ig heavy chain enhancer sequence. This construct was inserted downstream of a floxed beta-geo cassette and upstream of an IRES-PLAP cassette. Cre-mediated recombination of the STOP cassette is required for expression of the construct.
  • mutations:
  • Insertion
  • synonyms:
  • R26E2F1,
  • R26-betageo-E2F1,
  • R26-betageo-E2F1,
  • R26E2F1
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories