Primary Identifier | MGI:4940857 | Allele Type | Targeted |
Attribute String | Conditional ready, Humanized sequence, Inserted expressed sequence, Reporter | Gene | Gt(ROSA)26Sor |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A human E2F1 cDNA was cloned downstream of a murine Pim1 promoter with a duplicated Ig heavy chain enhancer sequence. This construct was inserted downstream of a floxed beta-geo cassette and upstream of an IRES-PLAP cassette. Cre-mediated recombination of the STOP cassette is required for expression of the construct. |