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Allele : Bmp4<tm2(tetO-Bmp4,lacZ)Jfm> bone morphogenetic protein 4; targeted mutation 2, James F Martin

Primary Identifier  MGI:4941211 Allele Type  Targeted
Attribute String  Hypomorph, Inducible, Inserted expressed sequence, Reporter Gene  Bmp4
Transmission  Germline Strain of Origin  129S4/SvJaeSor
Induced With  doxycycline/tetracycline Is Recombinase  false
Is Wild Type  false
molecularNote  The insertion of a construct consisting of a tetracycline operator, CMV promoter, Bmp4 cDNA, IRES lacZ, and FRT flanked pgk-neo cassette, and a poly-adenylation sequence was inserted in place of a 665 bp region that includes the basal promoter and exon1 of the gene. Analysis of p-Smad1/5/8 activity in heterozygous mice indicates this is a hypomorphic allele.
  • mutations:
  • Insertion
  • synonyms:
  • Bmp4<tetO>,
  • Bmp4<tetO>
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

1 Driven By

Trail: Allele

7 Publication categories

Trail: Allele