|  Help  |  About  |  Contact Us

Allele : Trp53<tm1.1Awbr> transformation related protein 53; targeted mutation 1.1, AW Braithwaite

Primary Identifier  MGI:4941040 Allele Type  Targeted
Attribute String  Hypomorph, Inserted expressed sequence Gene  Trp53
Transmission  Germline Strain of Origin  B6.Cg-Thy1<a>
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted upstream of exon 3. Exon 4 was replaced with a modified exon 4 that lacked 93 bps encoding amino acids 58 through 88 of the proline rich domain (mdeltapro). An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of the modified exon 4. Flp-mediated recombination removed the neo cassette.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Trp53mdeltapro,
  • p53<mdetlapro>,
  • Trp53mdeltapro,
  • p53<mdetlapro>
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

8 Publication categories

Trail: Allele