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Allele : Sost<tm1Lhe> sclerostin; targeted mutation 1, Lin He

Primary Identifier  MGI:4941817 Allele Type  Targeted
Attribute String  Null/knockout Gene  Sost
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  The genomic region of coding sequence (CDS) extending from exon 1 to exon 2 of the gene was replaced with a LacZ gene and a PGK-Neomycin cassette by targeted homologous recombination. RT-PCR confirmed absence of transcript, and Western blot confirmed absence of protein product in femur. This is a null allele.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories