Primary Identifier | MGI:4942191 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(CAG-EGFP,-PAX8/PPARG)1Rkoe |
Strain of Origin | FVB/NJ | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The CAG promoter drives expression of a floxed EGFP followed by the fusion of human PAX8 and PPARG. Cre-mediated recombination is required to remove the floxed EGFP cassette and allow for expression of the fusion protein. This fusion protein is expressed in 35% of human follicular thyroid carcinomas. |