| Primary Identifier | MGI:4942359 | Allele Type | Transgenic |
| Attribute String | Conditional ready, Inserted expressed sequence | Gene | Tg(Kit*D814V)3Roer |
| Strain of Origin | C57BL/6 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | This transgene consists of the mouse BAC clone RP23-274L11 which contains the entire Kit locus. The Kit locus in the BAC was modified by the insertion of a floxed stop cassette into intron 1 and the insertion of an A to T point mutation in exon 17 resulting in an aspartic acid to valine mutation at position 814. This mutation is homologous to the D816V mutation in humans. This line carries 2 copies of the transgene. Analysis of the residual vector backbone indicates the transgenes in this line may not be intact. |
