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Allele : Nrxn3<tm4.1Sud> neurexin III; targeted mutation 4.1, Thomas C Sudhof

Primary Identifier  MGI:4946102 Allele Type  Targeted
Attribute String  Modified isoform(s) Gene  Nrxn3
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed to insert a loxP site upstream of exon 20 (alternative splice site 4) followed by a frt-flanked neomycin resistance (neo) cassette, and a second loxP site downstream of exon 20. The less common splice acceptor sequence of exon 20 (TGTTTTTTAAACTTTAAAG) was substituted with a much more common one (TGTTTTTTCGTCTTCCTAG) to make the exon always incorporated in the transcript.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • Nrx3<ss4+>,
  • Nrx3<ss4+>,
  • NS4,
  • NS4
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

6 Publication categories

Trail: Allele