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Allele : Itga8<tm1.1Rdav> integrin alpha 8; targeted mutation 1.1, Ronald Davis

Primary Identifier  MGI:4948106 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Itga8
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed to insert a loxP site just upstream of exon 29, and also insert a loxP-flanked TK-neo cassette about 4kb downstream of the STOP codon in exon 30 of the Itga8 gene (also called integrin alpha 8, alpha8-integrin, or a8-integrin). Cre-mediated recombination removed the TK-neo selection cassette, leaving a single loxP site upstream of exon 29 and a single loxP site downstream of exon 30.
  • mutations:
  • Insertion
  • synonyms:
  • fA8,
  • floxed alpha8-integrin,
  • f(alpha8),
  • falpha8,
  • falpha8,
  • f(alpha8),
  • fA8,
  • floxed alpha8-integrin,
  • f(a8),
  • f(a8)
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

5 Publication categories