Primary Identifier | MGI:4948106 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Itga8 |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A targeting vector was designed to insert a loxP site just upstream of exon 29, and also insert a loxP-flanked TK-neo cassette about 4kb downstream of the STOP codon in exon 30 of the Itga8 gene (also called integrin alpha 8, alpha8-integrin, or a8-integrin). Cre-mediated recombination removed the TK-neo selection cassette, leaving a single loxP site upstream of exon 29 and a single loxP site downstream of exon 30. |