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Allele : Col1a1<tm1Dab> collagen, type I, alpha 1; targeted mutation 1, David A Brenner

Primary Identifier  MGI:4948122 Allele Type  Targeted
Attribute String  Hypomorph Gene  Col1a1
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed neo cassette was inserted between exon 1 and 2. This insertion is predicted to prevent formation of the 5' UTR stem-loop structure within intron 1. Reduced protein expression was confirmed by western blot analysis on mouse embryonic fibroblast extracts.
  • mutations:
  • Insertion
  • synonyms:
  • 5'-UTR SL,
  • 5'-UTR SL
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories