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Allele : Trp53<tm5.1Rivm> transformation related protein 53; targeted mutation 5.1, National Institute of Public Health and Environmental Protection (RIVM)
Primary Identifier  MGI:4947933 Allele Type  Targeted
Attribute String  Null/knockout Gene  Trp53
Transmission  Cell Line Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
description  This allele was originally generated in D3 cells containing Trp53tm1Tyj.
molecularNote  A loxP site flanked puromycin resistance gene cassette was inserted into intron 1. Glutamic acid codon 5 (GAG) in exon 2 was changed to a stop codon (TAG) (p.E5*). Cre-mediated recombination removed the puro cassette.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • Trp53<stop5>,
  • Trp53<stop5>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

2 Publication categories





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