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Allele : Trp53<tm6.1Rivm> transformation related protein 53; targeted mutation 6.1, National Institute of Public Health and Environmental Protection (RIVM)
Primary Identifier  MGI:4947934 Allele Type  Targeted
Gene  Trp53 Transmission  Cell Line
Strain of Origin  129S2/SvPas Is Recombinase  false
Is Wild Type  false
description  This allele was originally generated in D3 cells containing Trp53tm1Tyj.
molecularNote  A loxP site flanked puromycin resistance gene cassette was inserted into intron 1. Methionine codon 41 (ATG) in exon 2 was changed to isoleucine (ATA) (p.M41I). Cre-mediated recombination removed the puro cassette.
  • mutations:
  • Intragenic deletion,
  • Single point mutation
  • synonyms:
  • Trp53<M41I>,
  • Trp53<M41I>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

2 Publication categories





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