Primary Identifier | MGI:4947937 | Allele Type | Targeted |
Attribute String | Inducible, Recombinase | Gene | Lrig1 |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Induced With | tamoxifen | Is Recombinase | true |
Is Wild Type | false |
molecularNote | The targeting vector used for homologous recombination was generated by BAC recombineering. A tamoxifen-inducible cre (cre/ERT2) sequence, SV40 polyA signal, and an Frt-flanked PGK-neo cassette were targeted to the endogenous ATG site of Lrig1. Chimeras were crossed with Flpe-expressing animals to remove the neo from the germline. |