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Allele : Rr117<tm1.1Dje> regulatory region 117; targeted mutation 1.1, Douglas J Epstein
Primary Identifier  MGI:4948508 Allele Type  Targeted
Attribute String  Modified regulatory region Gene  Rr117
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted upstream of the 525 bp Shh brain enhancer 1 (SBE1) in intron 2. In addition, an FRT site flanked neomycin resistance gene cassette and a second loxP site were inserted immediately downstream of SBE1. Subsequent cre expression excised both SBE1 and the neo cassette.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Shh<tm1.1Dje>,
  • Shh<deltaSBE1>,
  • Shh<deltaSBE1>,
  • Shh<tm1.1Dje>
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1 Feature

Genome

0 Expresses

1 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories





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