| Primary Identifier | MGI:4950046 | Allele Type | Targeted |
| Gene | Esr1 | Transmission | Germline |
| Strain of Origin | 129S2/SvPas | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Mice lack the sequence in exon 8 that encodes the AF-2 core (amino acids 543 to 549; LLLEMLD). A floxed neo cassette used for selection was removed by cre-mediated recombination. The expression of a slightly smaller protein was confirmed by western blot analysis on uterus extracts. |
