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Allele : Ntrk3<tm1.1Tes> neurotrophic tyrosine kinase, receptor, type 3; targeted mutation 1.1, Lino Tessarollo
Primary Identifier  MGI:4950053 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ntrk3
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted upstream of exon 13b and a floxed ura/neomycin selection cassette was placed downstream of exon 14b. Cre expression results in removal of 2.5kb of sequence including both exons 13b and 14b. The deleted locus can no longer express the TrkC.T1 isoform. Full length product is expressed at a level of 1.6X normal however.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • TrkC.T1<->,
  • TrkC.T1<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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