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Allele : Creb1<tm3.1Gsc> cAMP responsive element binding protein 1; targeted mutation 3.1, Gunther Schutz

Primary Identifier	MGI:4999627	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Creb1
Transmission	Germline	Strain of Origin	129P2/OlaHsd
Is Recombinase	false	Is Wild Type	false

molecularNote

A single loxP site was inserted 5' to exon 10 and a loxP flanked neomycin and thymidine kinase cassette was inserted 3' to exon 10. Cre mediated recombination removed the selection cassette and exon 10.

mutations:
Intragenic deletion,
Insertion

cellLines:
Not Specified

synonyms:
Creb1<->,
Creb1<->

earliestPublication:
Mantamadiotis T, et al. (2002) Disruption of CREB function in brain leads to neurodegeneration. Nat Genet 31(1):47-54

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

6 Publication categories

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