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Allele : Cryab<tm1.1Ady> crystallin, alpha B; targeted mutation 1.1, Usha P Andley
Primary Identifier  MGI:4999580 Allele Type  Targeted
Attribute String  Humanized sequence Gene  Cryab
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 3 was replaced with one in which an A to G transition results in the amino acid transition of arginine to glycine at position 120 (R120G), mimicking a mutation associated with cataracts and desmin-related myopathy (DRM) in humans. Cre-mediated recombination removed the floxed neo cassette inserted downstream of the modified exon 3.
  • mutations:
  • Single point mutation,
  • Insertion
  • synonyms:
  • alphaB-R120G,
  • alphaB-R120G
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

13 Publication categories





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